Systems analysis of Ran transport.

A systems analysis of importin-α–β mediated nuclear protein import

Importin-beta (Impbeta) is a major transport receptor for Ran-dependent import of nuclear cargo. Impbeta can bind cargo directly or through an adaptor such as Importin-alpha (Impalpha). Factors involved in nuclear transport have been well studied, but systems analysis can offer further insight into regulatory mechanisms. We used computer simulation and real-time assays in intact cells to examin...

Numerical Analysis of Sediment Transport in Sewer Pipe

The efficiency and economical performance of sewer systems is an essential issue in urban drainage. The need for sewers to carry sediment has been recognized for many years. One of the main problems in designing sewerage systems is the sediment deposition. Sedimentation in sewers occurs regularly according to the alternating natural flow. The present study investigates the hydraulic characteris...

Targeting of Ran: variation on a common theme?

The Ran GTPase plays a key role in nucleocytoplasmic transport. In its GTP-bound form, it directly interacts with members of the importin beta family of nuclear transport receptors and modulates their association with cargo. Work in cell-free higher-eukaryote systems has demonstrated additional roles for Ran in spindle and nuclear envelope formation during mitosis. However, until recently, no R...

Taxonomy of Global Air Transport

Data from the United Nations and the International Civil Aviation Organization Information Systems were used as a base for characterizing, classifying and comparing air transport demand and supply features of 156 countries. Relevant data from 1980 were chosen to reflect five sets of characteristics namely, air transport, 50cm-economic status, population demography, geographical and environmenta...

Estimating Missing Traffic Volume Using Low Multilinear Rank Tensor Completion